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The availability of penicillin during the war prevented thousands of deaths from gas gangrene and other infections. Once the penicillin production had begun, the race was on to discover its molecular structure so that it could be synthetically produced. In the mid-1940s, English researcher Dorothy Crowfoot Hodgkin began a single- crystal study of penicillin using x-ray crystallography...
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In the mid-1940s, English researcher Dorothy Crowfoot Hodgkin began a single- crystal study of penicillin using x-ray crystallography. This technique obtains data from repeated x-rays to calculate the positions of the atoms in the basic unit of the crystal. Hodgkin was able to use an early IBM card-punch computer to complete the many mathematical computations required to carry out the experiment...
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