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Topic: |
Science
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Number of pages / Number of words: |
28 / 7727 |
Essay's paper body
The bacteria then travel to lungs and
establish an infection (1). In the lungs they ?rst encounter
alveolar macrophage, which has the ability to destroy most
potential invaders. However, M. tuberculosis has the extra-
ordinary ability to persist and even replicate in this extremely
hostile environment, where most other pathogens would perish...
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tuberculosis seems to have evolved e?ective strategies to
survive most of the macrophage killing mechanisms.
In most common clinical pattern of tuberculosis, T
lymphocytes get activated after infection and this causes
in?ltration of activated macrophages to the site of infection.
These lymphocytes arrest the organism inside a granuloma-
tous lesion called a tubercle...
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