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| Topic: |
Science
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| Number of pages / Number of words: |
5 / 1242 |
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By altering the chemical composition of the mevastatin molecule, various statin drugs were later created. Fluvastatin was synthetically derived from mevastatin by replacing the decalin ring of the fungal compounds with aromatic rings. Pravastatin was created through microbial alterations. Finally, synthetic alteration of the acyl group on C1 of mevastatin yields simvastatin, marketed commercially as Zocor (Gilson)...
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Finally, synthetic alteration of the acyl group on C1 of mevastatin yields simvastatin, marketed commercially as Zocor (Gilson).
As the most publicized statin drug, boasting television and print ads, simvastatin – or Zocor as it is more commonly known – has come into the public’s attention as an important drug in treating hypercholesterolemia...
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