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| Topic: |
Science
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| Number of pages / Number of words: |
8 / 2006 |
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However, if one of the six genes is altered, forms of hemoglobin other than hemoglobin A will result (http://sickle.bwh.harvard.edu/scd_background.html, 2008).
The beta-globin gene that is found on the short arm of chromosome eleven is the determinant of sickle cell anemia. A slight alteration in just one nitrogenous base in the DNA sequence coding of this gene is simply all that is necessary to cause a lifetime of medical complications...
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A slight alteration in just one nitrogenous base in the DNA sequence coding of this gene is simply all that is necessary to cause a lifetime of medical complications. This change causes a point mutation in the beta-globin chain. In other words, glutamic acid, an amino acid that normally fills the sixth position in the beta chain, is replaced by another amino acid called valine (Biology 11, 2002, p...
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