Buy custom Physiologic Effects of Insulin
Essay's paper info
Topic: |
Science
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Number of pages / Number of words: |
6 / 1468 |
Essay's paper body
In many tissues - muscle being a prime example - the
major transporter used for uptake of glucose (called GLUT4) is made available in the
plasma membrane through the action of insulin.
In the absence
of insulin, GLUT4 glucose
transporters are present in cytoplasmic vesicles,
where they useless for transporting glucose...
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When blood levels
of insulin decrease and insulin receptors are no
longer occupied, the glucose transporters are
recycled back into the cytoplasm.
The animation to the right depicts how
insulin signalling leads to translocation of
glucose transporters from the cytoplasm into
the plasma membrane, allowing glucose
(small blue balls) to enter the cell...
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