Buy custom Non Composites Scaffolds For Tissue Engineering
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| Topic: |
Science
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| Number of pages / Number of words: |
16 / 4372 |
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Even though HA ceramics are highly biocompatible and have a high osteogenic
potential, the brittleness, fatigue failure in the body and bad biodegradability limits their clinical
application only for unloading bearing repair and substitute (1).
Biodegradable synthetic polyesters, such as poly (lactic acid)(PLA), poly(glycolic
acid)(PGA) and their copolymer poly(lactide-co-glycolide)(PLGA), are been used in number of
clinical applications...
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PLGA is also one of the prospective materials and is used as a construct
material for bone tissue engineering. By controlling the molecular weight and the unit ratio of
lactide to glycolide in the copolymer the mechanical properties and biodegradation rate of PLGA
can be manipulated. PLGA when used in bone tissue engineering have proven to be
biocompatible, non-toxic and non-inflammatory (3, 4)...
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