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Science
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Number of pages / Number of words: |
10 / 2627 |
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This pattern occurs in several other places of the pedigree, and indicates a recessive mode of inheritance. From the biochemical nature of the defect, scientists have determined that hemophilia is a recessive trait. All the affected individuals are sons, strongly suggesting that the defect is a sex linkage trait...
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Since males are hemizygous for the X chromosome, more males than females should have the phenotype of a sex-linked recessive trait because males do not have a second X chromosome that might carry the normal allele. The first prediction that we can make from this is that all males get their X chromosomes from their mothers; affected males should be the offspring of carrier, heterozygous, females...
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