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Topic: Science
Number of pages / Number of words: 19 / 5284
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that helps maintain arterial pressure at or near normal level even when salt intake is increased

? When system functions normally, arterial pressure rises no more than 4-6mmHg in response to as much as 50-fold increase in salt intake

Angiotensin Converting Enzyme Inhibitor (ACEI)

? Enalapril or lisinopril are recommended when first-line agents (diuretics or beta-blockers) are contraindicated or ineffective

? ACEI suppress prod'n of angiotensin II, the most vasoactive product of RAAS

? Inihibition of ACE ? decreased systemic arteriolar resistance and mean diastolic and systolic BP

o In CHF, ACE inhibition = decreased afterload and HR as well as increased CO, SV, and stroke work

? ACE catalyzes other physiologic reactions incl...


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that helps maintain arterial pressure at or near normal level even when salt intake is increased

? When system functions normally, arterial pressure rises no more than 4-6mmHg in response to as much as 50-fold increase in salt intake

Angiotensin Converting Enzyme Inhibitor (ACEI)

? Enalapril or lisinopril are recommended when first-line agents (diuretics or beta-blockers) are contraindicated or ineffective

? ACEI suppress prod'n of angiotensin II, the most vasoactive product of RAAS

? Inihibition of ACE ? decreased systemic arteriolar resistance and mean diastolic and systolic BP

o In CHF, ACE inhibition = decreased afterload and HR as well as increased CO, SV, and stroke work

? ACE catalyzes other physiologic reactions incl...


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