Buy custom Ezrin silencing by small hairpin RNA reverses metastatic behaviors of human breast cancer cells.
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Science
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| Number of pages / Number of words: |
3 / 775 |
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This correlation is somehow inversed to the function of ezrin shRNAs upon ezrin protein. It is inversed because when ezrin protein is over expressed it seems to contribute to metastasis whereas when ezrin protein is exposed to a silencing gene (ezrin shRNAs) it suppresses metastasis. E-cadherin on the other hand, contributes to metastasis when it is deregulated or loss and when expressed, metastasis does not occur...
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E-cadherin on the other hand, contributes to metastasis when it is deregulated or loss and when expressed, metastasis does not occur.
E-cadherin is regulated through a series of phosphorylation states of tyrosine in ?-catenin. This type of phosphorylation is known to be very important for cell growth because it makes it possible for a regulatory mechanism to take place for E-cadherin in cell adhesion...
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Protein Brochure
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Ezrin silencing by small hairpin RNA reverses metastatic behaviors of human breast cancer cells.
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