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| Topic: |
Science
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| Number of pages / Number of words: |
10 / 2704 |
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Nucleotides are the chemical building blocks of DNA. There are only four nucleotides that make up every single strand of DNA in every living creature: adenine, guanine, cytosine, and thymine.
Any genetic material being tested is first labeled with a fluorescent marker. When the marked DNA is applied to the DNA chip, any strands of marked DNA whose nucleotide sequence is complimentary to the sequence of a given DNA probe, will hybridize to the DNA probe and hence "stick" to the chip...
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Any other marked DNA that does not compliment one of the particular sequences of a probe on the chip, will not stick, and can be washed away. Even DNA segments that partially complement and bond with the DNA of the probe, will be washed away with a 97 percent success rate.
Carefully designed arrays of DNA probes can give the DNA chip the ability to represent an entire genes nucleotide sequence...
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