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To generate high quality sequencing , additional sequencing is needed to close gaps, reduce mistakes and allow only a single error in 10,000 bases. The finished version will provide an estimated eight to nine times the coverage of each chromosome. Thus far, high quality sequences have been generated for human chromosomes 21 and 22...
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Thus far, high quality sequences have been generated for human chromosomes 21 and 22.
Chromosome 22
The euchromatic portion of chromosome 22 is estimated to be a 33.5-Mb structure comprising at least 545 and possibly up to 1000 genes, ranging in size from 1000 to 583,000 bases. Chromosome 22's sequences of DNA is of extremely high quality with an error rate of less than 1 in 50,000 bases...
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