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Subjects were aged 18?55 years and were following a stable insulin administration schedule (for at least 2 months) involving two to three injections daily. Screening and prerandomization HbA1c values were between 7.0 and 11.9%, with fasting plasma C-peptide 0.2 pmol/ml. Body weight of each subject was 80?130% of ideal...
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Body weight of each subject was 80?130% of ideal. Subjects were nonsmokers (for at least 6 months), gave normal results on a chest x-ray and pulmonary function tests, and had an electrocardiogram showing normal sinus rhythm. All subjects performed blood glucose monitoring four times daily: before breakfast, before lunch, before supper, and at bedtime...
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