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(Gene Clinics, 2000). If the mutation exists in someone's genetic makeup it is considered a dominant trait and can be passed down generation to generation as long as it remains dominant. The mutation may also be passed down as a recessive gene in the genetic makeup.
The risk that a sibling will inherit the cancer predisposing BRCA1 and BRCA2 mutation is fifty percent if at least one parent had the BRCA1 or BRCA2 cancer predisposing mutation as well...
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If one sibling inherited the mutation it does not mean that the other siblings will also inherit the mutation. However, the risk of developing the cancer depends upon the kind of mutation, the gender of the individual, and the person's age. (Gene Clinics, 2000) Studies showed that the BRCA1 cancer predisposing gene is linked to forty five percent of site specific related breast cancer and thirty five percent of site specific cases were related to the BRCA2 gene...
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